Single Genetic Tweak Turns Mosquitoes into Non‑Transmissible Malaria Vectors

THE SCIENTIST

Scientists from UC San Diego used CRISPR to replace one amino acid in a mosquito protein (FREP1), rendering them resistant to both Pf and Pv malaria. A gene‑drive-like allelic system spreads this trait—blocking transmission while preserving mosquito fitness. A groundbreaking path to malaria control.