Scientists from UC San Diego used CRISPR to replace one amino acid in a mosquito protein (FREP1), rendering them resistant to both Pf and Pv malaria. A gene‑drive-like allelic system spreads this trait—blocking transmission while preserving mosquito fitness. A groundbreaking path to malaria control.
(c) David Clode/Unsplash CC0
(c) David Clode/Unsplash CC0

Un solo cambio genético convierte a mosquitos en impasivos al paludismo

THE SCIENTIST

Investigadores de UC San Diego usaron CRISPR para sustituir un aminoácido en la proteína FREP1 de mosquitos, haciéndolos resistentes al artefacto de la malaria P. falciparum y P. vivax. Un sistema tipo «drive» genética propaga este rasgo sin afectar su salud. Un avance transformador para el control del paludismo.

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