A randomized controlled trial gave 37 patients with alcohol use disorder either psilocybin or a placebo and then examined their DNA methylation — chemical changes that regulate gene activity without altering DNA itself. Psilocybin produced significant changes in genes linked to serotonin signaling, immune response, and inflammation, pointing toward biological mechanisms behind its therapeutic effects.
(c) Nikola Tomašić

Ang psilocybin ay nag-iiwan ng nasusukat na epigenetic na marka sa mga taong may alcohol use disorder

MEDICAL XPRESS

Isang randomized controlled trial na inilathala sa Translational Psychiatry ang nagbigay ng psilocybin o placebo sa 37 pasyenteng may alcohol use disorder, pagkatapos ay sinuri ang kanilang DNA methylation — mga kemikal na pagbabago na nag-aayos ng aktibidad ng gene nang hindi binabago ang DNA mismo. Nagdulot ang psilocybin ng malalaking pagbabago sa mga gene na kaugnay ng serotonin signaling, immune response, at pamamaga.

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